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A contact ATR spectrum is collected from human skin. |
Remspec’s fiber-optic technology is ideal for non-invasive analysis of soft tissue.
Contact ATR spectra are obtained by pressing an ATR crystal firmly against the target tissue, giving the mid-IR spectrum of the surface layer to a depth of a few microns. Changes due to tissue degradation, or following treatment with lotions etc., can be characterized rapidly. |
A flat-tipped ATR crystal is used for contact ATR of soft tissue to allow for good optical contact with minimal tissue damage. |
| Typical mid-IR spectra of soft tissue include characteristic "amide I" and "amide II" bands between 1700 and 1600 cm-1; these features originate from proteins. |
TissueView spectra of human skin (navy trace) and human cartilage (red trace) |
Selected References A chemometric analysis for evaluation of early-stage cartilage degradation by infrared fiber-optic probe spectroscopy, G Li,M Thomson,E Dicarlo,X Yang,B Nestor,MP Bostrom,NP Camacho, Appl Spectrosc. 2005 Dec;59(12):1527-33.
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